SGPT Full Form – Definition, Functions, Causes, Reduction

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SGPT Full Form

SGPT Full Form: SGPT stands for Serum Glutamic Pyruvic Transaminase. This is an enzyme that is primarily present in the liver cells. This enzyme is also commonly known as Alanine aminotransferase (ALT). It is one of the key liver function tests that helps determine the health of the liver.

In this article, we will explore the full form of SGPT in detail. We will also understand its function, normal range, causes of elevated levels, and how to reduce high SGPT levels.

SGPT Full Form – Functions

The following are the functions of SGPT:

  • To help in the metabolism of proteins in the liver cells
  • Transferring an amino group from alanine to alpha-ketoglutarate, which results in the formation of pyruvate and glutamate. The cells then convert Pyruvate into energy. Glutamate is further metabolized in the liver to produce energy or to form urea.

SGPT Full Form – Normal Range of SGPT

The normal range of SGPT in the blood varies on various factors. These include the age, sex, and overall health of the individual. However, in general, the normal range of SGPT is between 10 to 40 units per liter (U/L) for men. For women, this range is between 7 to 35 U/L. Elevated levels of SGPT may indicate liver damage or disease.

CategoryRange (units/liter)
Men10 – 40
Women7 – 35

Causes of Elevated SGPT Levels

A number of factors can cause increased levels of SGPT, including the following:

  1. Liver Disease: A number of liver diseases can cause SGPT levels to rise. These include Hepatitis B or C, alcoholic liver disease, non-alcoholic fatty liver disease, and liver cirrhosis.
  2. Medications: Certain medications can cause liver damage. An example would be statins used to lower cholesterol levels.
  3. Alcohol Consumption: Excessive alcohol consumption can cause inflammation and damage to the liver cells, leading to elevated SGPT levels.
  4. Obesity: Obesity and insulin resistance can cause non-alcoholic fatty liver disease, which can increase SGPT levels.
  5. Viral Infections: Viral infections that can cause liver inflammation can lead to elevated SGPT levels. Some of these are the Epstein-Barr virus, cytomegalovirus, and herpes simplex virus.
  6. Genetic Factors: Genetic factors can also contribute to elevated SGPT levels in some individuals.

How to Reduce High SGPT Levels

If you have high SGPT levels, it is important to identify the underlying cause and take steps to reduce it. Some of the ways to reduce high SGPT levels include:

  1. Lifestyle Changes: Make lifestyle changes such as reducing alcohol consumption, losing weight, and following a healthy diet.
  2. Medications: Doctors can prescribe medications to treat underlying medical conditions that are causing elevated SGPT levels.
  3. Herbal Supplements: Taking certain herbal supplements such as milk thistle, dandelion root, and artichoke extract have liver-protective properties.
  4. Liver Detoxification: Liver detoxification through the use of specific diets, supplements, and therapies.
  5. Regular Monitoring: It is important that you regularly monitor SGPT levels and take appropriate action if they are elevated.

SGPT Full Form – Conclusion

SGPT is a liver enzyme that plays an important role in the metabolism of proteins in the liver cells. Elevated levels of SGPT may indicate liver damage or disease and can happen due to various factors such as liver disease, medication, alcohol consumption, obesity, viral infections, and genetic factors. You can bring down high levels of SGPT through lifestyle changes, medication, herbal supplements, liver detoxification, and regular monitoring.

SGPT Full Form – Frequently Asked Questions

Q1. What is the full form of SGPT?

A1. SGPT stands for Serum Glutamic Pyruvic Transaminase.

Q2. What is the use of SGPT?

A2. SGPT helps the metabolism of proteins in cells.

Q3. What is the normal range of SGPT in men?

A3. The range of SGPT in men in


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