The correct order to form a meaningful sentence is EBADC. Part E introduces the main idea of the sentence, stating that doubts exist. Part B specifies what the doubt is related to (accordingly, EB forms a necessary pair). The doubt is related to the effectiveness of something. Part A further specifies what the doubts pertain to, which is the new drug. The doubt is related to the effectiveness of the new drug. Parts D and C specify the action or purpose related to the new drug, which is its use in treating the disease. Hence, (b) is the correct answer.
The complete sentence is: There are doubts about the effectiveness of the new drug in treating the disease.